Yoh Takuwa Selected Research

LC 6

5/2011	Similar changes of hypothalamic feeding-regulating peptides mRNAs and plasma leptin levels in PTHrP-, LIF-secreting tumors-induced cachectic rats and adjuvant arthritic rats.
1/2007	Parathyroid hormone-related protein induces cachectic syndromes without directly modulating the expression of hypothalamic feeding-regulating peptides.

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Yoh Takuwa Research Topics

Disease

12	Neoplasms (Cancer) 01/2018 - 06/2002
7	Atherosclerosis 12/2019 - 06/2002
6	Inflammation (Inflammations) 01/2020 - 06/2002
4	Fibrosis (Cirrhosis) 01/2018 - 02/2010
3	Thrombosis (Thrombus) 10/2017 - 01/2004
3	Anorexia 05/2011 - 01/2007
3	Vascular Remodeling 09/2008 - 06/2002
2	Starvation 01/2022 - 07/2018
2	Vascular System Injuries 01/2019 - 01/2004
2	Insulin Resistance 09/2014 - 12/2012
2	Anaphylaxis (Anaphylactic Shock) 11/2013 - 10/2012
2	Aortic Aneurysm (Aneurysm, Aortic) 10/2012 - 12/2009
2	Body Weight (Weight, Body) 10/2012 - 05/2011
2	Cachexia 05/2011 - 12/2007
2	Arthritis (Polyarthritis) 05/2011 - 03/2009
2	Melanoma (Melanoma, Malignant) 05/2011 - 09/2003
2	Stomach Neoplasms (Stomach Cancer) 01/2006 - 12/2004
2	Neoplasm Metastasis (Metastasis) 01/2006 - 09/2003
1	Coronary Disease (Coronary Heart Disease) 12/2019
1	Hyperplasia 01/2019
1	Alzheimer Disease (Alzheimer's Disease) 01/2018
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2018
1	Hepatocellular Carcinoma (Hepatoma) 12/2017
1	Liver Neoplasms (Liver Cancer) 12/2017
1	Cardiomegaly (Heart Hypertrophy) 01/2017
1	Acute Lung Injury 09/2016
1	Pulmonary Edema 09/2016
1	Type 2 Diabetes Mellitus (MODY) 09/2014
1	Portal Hypertension 10/2012
1	Muscle Spasticity (Spastic) 08/2011
1	Diabetic Angiopathies (Diabetic Angiopathy) 06/2011
1	Hypercalcemia (Milk Alkali Syndrome) 05/2011
1	Lung Neoplasms (Lung Cancer) 05/2011
1	Atherosclerotic Plaque (Atheroma) 11/2010

Drug/Important Bio-Agent (IBA)

9	Sphingosine-1-Phosphate ReceptorsIBA 11/2013 - 09/2003
6	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2018 - 08/2003
6	rho-Associated KinasesIBA 10/2012 - 07/2002
4	SphingosineIBA 12/2019 - 05/2008
4	LysophospholipidsIBA 01/2018 - 06/2002
4	sphingosine kinaseIBA 12/2017 - 02/2010
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2014 - 03/2009
4	lysophosphatidic acidIBA 01/2013 - 04/2003
3	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2010
3	LipidsIBA 12/2019 - 01/2009
3	Matrix Metalloproteinase 14 (MT1-MMP)IBA 01/2014 - 10/2009
3	Thromboplastin (Tissue Factor)IBA 01/2014 - 07/2002
3	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2010 - 08/2003
3	LigandsIBA 05/2007 - 08/2003
2	FibrinIBA 01/2020 - 10/2017
2	CholesterolIBA 12/2019 - 11/2010
2	SphingolipidsIBA 12/2019 - 11/2010
2	Interleukin-6 (Interleukin 6)IBA 01/2019 - 01/2017
2	Angiotensin IIIBA 01/2017 - 10/2012
2	CytokinesIBA 01/2013 - 11/2010
2	LC 6IBA 05/2011 - 01/2007
2	Parathyroid Hormone-Related ProteinIBA 05/2011 - 01/2007
2	LeptinIBA 05/2011 - 01/2007
2	Peptides (Polypeptides)IBA 05/2011 - 01/2007
1	ClathrinIBA 01/2022
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 01/2022
1	Transcription Factors (Transcription Factor)IBA 07/2018
1	Amyloid (Amyloid Fibrils)IBA 01/2018
1	Interleukin-13IBA 01/2018
1	Bleomycin (Blenoxane)FDA LinkGeneric 01/2018
1	3,7,11,15- tetramethyl- 2,4,6,10,14- hexadecapentaenoic acidIBA 12/2017
1	(2E,4E,6E,10E)- 3,7,11,15- tetramethyl- 2,4,6,10,14- hexadecapentaenoic acidIBA 12/2017
1	Diethylnitrosamine (N-Nitrosodiethylamine)IBA 12/2017
1	MetalsIBA 10/2017
1	Tyrosine (L-Tyrosine)FDA Link 01/2017
1	Phosphates (Orthophosphate)IBA 01/2017
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2017
1	fluorescein isothiocyanate dextranIBA 09/2016
1	LipopolysaccharidesIBA 09/2016
1	Evans Blue (Blue, Evans)FDA Link 09/2016
1	Selenoprotein PIBA 09/2014
1	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 11/2013
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 11/2013
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2013
1	Fibronectins (Fibronectin)IBA 01/2013
1	CollagenIBA 01/2013
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 12/2012
1	JNK Mitogen-Activated Protein KinasesIBA 12/2012
1	CeramidesIBA 12/2012
1	salicylhydroxamic acid (SHAM)IBA 10/2012
1	JTE 013IBA 10/2012
1	Verapamil (Calan)FDA LinkGeneric 08/2011
1	fasudil (AT 877)IBA 08/2011
1	Nitroglycerin (Dynamite)FDA LinkGeneric 08/2011
1	Myosin Light Chains (Myosin Essential Light Chain)IBA 08/2011
1	Advanced Glycation End ProductsIBA 06/2011
1	NADPH Oxidases (NAD(P)H oxidase)IBA 06/2011
1	hydroxide ionIBA 05/2011
1	Apolipoproteins E (ApoE)IBA 11/2010

Therapy/Procedure

3	Stents 01/2020 - 12/2009
3	Injections 01/2018 - 05/2010
2	Ligation 01/2019 - 10/2012
1	Therapeutics 01/2018
1	Intravenous Infusions 10/2012
1	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 08/2011
1	Oral Administration 05/2011